Hydroxyethyl strach or gelatin, wich is safer for the kidneys? Repository

Hydroxyethyl strach or gelatin, wich is safer for the kidneys?

D.W. Shinta and Junaidi Khotib, NIDN. 0022107001 and Mahardian Rahmadi, NIDN. 0014038102 and B. Suprapti (2018) Hydroxyethyl strach or gelatin, wich is safer for the kidneys? In: Proceedings of the 17th Asian Conference on Clinical Pharmacy: Unity and Diversity and the standardisation of Clinical Pharmacy Services. CRC Press, Yogyakarta, pp. 281-286.

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Abstract

The aim of thisstudy was tocompare the effects of HES 200/0.5 and gelatin in the kidneys with a dose of < 20 ml/kg/day. This is an observational study conducted in patients who underwent elective surgery at Dr. Soetomo Hospital with the bleeding condition being 15-30% of EBV (Estimated Blood Volume) and a resuscitation fluid of HES 200/0.5 or modified fluid gelatin. The observed parameters were the ratio of NAG/urinary creatinineand serum creatinine. The results indicated that there was a significant increase in the NAG/creatinine ratio in the HES 200/0.5 group (p = 0.0004), with no significant increase in modified gelatin. By contrast, the gelatin group showed a significant increase in serum creatinine (p < 0.0001 ) compared with the HES group. However, the increase in the NAG/urinary creatinine ratio and serum creatinine in both groups was within the normal limits. HES 200/0.5 or modified gelatin at a dose of < 20 ml/kg/day in surgery patients does not lead to changes in kidney function

Item Type:

Book Section

Subjects:

R Medicine
R Medicine > RS Pharmacy and materia medica

Divisions:

05. Fakultas Farmasi

Creators: