NITHA DWI AGUSTIN KUSUMAWATI, 050710237 (2012) POLA PENGGUNAAN ANTIBIOTIK PADA PASIEN STROKE PERDARAHAN INTRASEREBRAL YANG DILAKUKAN CRANIOTOMY (Penelitian dilakukan di Instalasi Rawat Inap Ilmu Penyakit Saraf RSUD Dr.Soetomo Surabaya). Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Stroke is the leading cause of mortality after cardiovascular disease and cancer. Stroke is defined by a syndrome characterized with a focal neurologic deficit occuring acutely during more than 24 hours and caused by cerebral-circulation dissorder. Intracranial hemorrhage stroke is the result of vascular rupture in brain parenchim. Craniotomy is one of the surgery intervention therapy of intracranial hemorrhage stroke with infection as the post-operative complication. Craniotomy has low incidence of surgical site infection rate but high risk in mortality. Therefore prophylactic and therapy antibiotic is necessary to be administered in this case. The purpose of this study is to analyze the profile use of antibiotic received in intracerebral hemorrhage stroke patient with craniotomy.A retrospective methods with descriptive analysis was performed in 30 patients obtained in January 2010-December 2010 periode who diagnosed intracerebral hemorrhage stroke with craniotomy.The 76,7 % commonly used prophylactic antibiotic is fosfomycin. Moreover 73,3 % patients received fosfomycin as empiric antibiotic. The duration of empiric- antibiotic adminsitration commonly in 1-5 days as 70,2%. There is inproper selection in definitive antibiotic. This study found that there are DRPs respectively the patient did not receive proper antibiotic based on culture test, patient did not receive the right dossage regimentation, and there is inproper selection for antibiotic.

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