Rohdiya Wahyuni and Isnaeni and Asri Darmawati (2014) Prospektif Kombinasi Susu Probiotik Lactobacillus acidophilus dan Bifidobacterium bifidum Sebagai Sediaan Anti Diare. Berkala Ilmiah Kimia Farmasi, 3 (1). pp. 42-47. ISSN 2302-8270

	Text (FULLTEXT) C-31b.pdf Download (377kB)
	Text (PEER REVIEW) Val C-31.pdf Download (1MB)

Abstract

In the course of our screening program for anti diarrheal bacterial – Escheria coli, Salmonella typhimurium, and Vibrio cholerae agents from fermented probiotic milk, Lactobacillus acidophilus FNCC-0051 and Bifidobacterium bifidum as a potential probiotic were picked out for further investigation. Each probiotic microorganism was prepared as fermented milk by using 15% skim milk. Inhibition potency of the fermented milk that consisted of both probiotic microorganisms at 1:9, 2:8, 3:7, 4:6, 5:5, 6:4, 7:3, 8:2, and 9:1 ratio was assayed against diarrheal causing bacteria. The combination of two fermented probiotic milk showed strong inhibition against test bacteria at ratio of 4:6 and the MIC is 30%. On the other hands, total plate count of the combination is 108 cfu/mL, is comply with the requirement for intestine as target side of action. Thus, the combination was considered of great potential to develop as an anti diarrheal preparation.

Actions (login required)

View Item