Acronyculatin P, A New Isoprenylated Acetophenone from the Stem Bark of Acronychia pedunculata

Mulyadi Tanjung and Intan Nurmalasari and Aisyah Kanti Wilujeng and Ratih Dewi Saputri and Fida Rachmadiarti and Tjitjik Srie Tjahjandarie (2018) Acronyculatin P, A New Isoprenylated Acetophenone from the Stem Bark of Acronychia pedunculata. Natura Product Sciences, 24 (4). pp. 284-287. ISSN 1226-3907

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Official URL: https://synapse.koreamed.org/DOIx.php?id=10.20307/...

Abstract

Abstract − A new isoprenylated acetophenone, acronyculatin P (1) as well as two known compounds, 3',5'diisoprenyl-2',4'-dihydroxy-6'-methoxyphenylethanone (2) and 3'-isoprenyl-2',4',6'-trihydroxyphenylethanone (3) were isolated from the stem bark of Acronychia pedunculata (L.) Miq. The structures were determined by HRESIMS, 1D and 2D NMR. The inhibitory activity of the isoprenylated acetophenone derivatives against murine leukemia P-388 cells showed compound 1 moderate activity with IC 50 15.42 µM.

Item Type: Article
Uncontrolled Keywords: Acronyculatin P, isoprenylated acetophenone, Acronychia pedunculata, P-388 cells
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsNIM
Mulyadi TanjungNIDN0022046503
Intan NurmalasariUNSPECIFIED
Aisyah Kanti WilujengUNSPECIFIED
Ratih Dewi SaputriUNSPECIFIED
Fida RachmadiartiUNSPECIFIED
Tjitjik Srie TjahjandarieNIDN0006026502
Depositing User: Mr Vega Andi Budiman
Date Deposited: 2015
Last Modified: 13 Mar 2020 02:28
URI: http://repository.unair.ac.id/id/eprint/90966
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