ASTRID FEBRINA SAIMORA, 051511133214 (2019) PENGARUH SUHU INLET TERHADAP EFISIENSI ENKAPSULASI Lactobacillus casei DALAM MIKROPARTIKEL (Dengan Matriks Kombinasi Kopolimer Asam Metakrilat Tipe L dan Tipe S serta Laju Alir Bahan 10 ml/menit). Skripsi thesis, Universitas Airlangga.

	Text FF F 19 19 Sai p ABSTRAK.pdf Download (30kB)
	Text FF F 19 19 Sai p DAFTAR ISI.pdf Download (39kB)
	Text FF F 19 19 Sai p DAFTAR PUSTAKA.pdf Download (65kB)
	Text (FULLTEXT) FF F 19 19 Sai p.pdf Restricted to Registered users only until 20 November 2022. Download (704kB) | Request a copy

Abstract

Lactobacillus casei is a probiotic that provides health benefit for human being by improving intestinal microbial balance if it’s taken as much as 106 – 109 cfu/g. Drug delivery system like microparticle is needed to protect Lactobacillus casei from gastric condition so it can release the probiotics in intestine. A matrix that is resistance to acid condition and dissolves in base condition is needed to protect Lactobacillus casei in the microparticle. The combination of methacrylic acid copolymer L-type and S-type is used as matrix in this research. The aim of this research is to know the effect of inlet temperature to encapsulation efficiency Lactobacillus casei in microparticle with a combination of methacrylic acid copolymer Ltype and S-type as a matrix. Microparticles were made by spray dry method with inlet temperature 100, 120, and 140 oC and feed flow rate 10 ml/min. The encapsulation effiency test was done after the microparticles were obtained. The encapsulation effiency at each inlet temperature were 25,93%; 24,65%; and 25,10%, respectively. The statistic analysis One Way ANOVA was done and the result showed that no significant difference was found on the encapsulation efficiencies of the three inlet temperatures.

Actions (login required)

View Item