Management for a Patient with Barret’s Esophagus: A Case Report

Muhammad Miftahussurur and Iswan Abbas Nusi and Poernomo Boedi Setiawan and Herry Purbayu and Titong Sugihartono and Ummi Maimunah and Ulfa Kholili and Budi Widodo and Husin Thamrin and Amie Vidyani (2017) Management for a Patient with Barret’s Esophagus: A Case Report. In: Proceedings of Surabaya International Physiology Seminar. SCITEPREES-Science and Technology Publications, Lda., Surabaya, pp. 438-445. ISBN 978-989-758-340-7

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Abstract

Barrett's esophagus (BE) is a displacement of the squamocolumnar border (SCJ) site to proximal to the gastroesophageal junction (GEJ) accompanied by the presence of intestinal metaplasia. BE develops when reflux-induced stomach acid destroys the squamous epithelial layer of the esophagus and this lesion heals via a metaplasia process in which the damaged squamous epithelial layer is replaced by columnar colon-type epithelium. BE prevalence in the general population is about 1.6-1.7%. Patients with gastroesophageal reflux disease (GERD) may progress to BE. This report concerns two cases of patients with Barrett's esophagus. In both these patients BE was found without dysplasia. A diagnosis was made on the basis of anamnesis, physical examination, laboratory, radiological, endoscopy and anatomical pathology. The management of BE is aimed at three main objectives: reduction of symptoms due to GERD, avoiding progression to strictures and ulcers, and preventing progression to adenocarcinom a. Both patients were given a PPI, a prokinetic and chemoprevention NSAID which achieved clinical improvement. Neither patient had ablation, photodynamic or mucosal resection. BE survival is much better than in groups without BE (5 years survival 61% vs. 28%, P = 0.001)

Item Type: Book Section
Uncontrolled Keywords: Barrett's esophagus, squamocolumnar, gastroesophageal, intestinal metaplasia, gastroesophageal reflux disease
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine
Divisions: 01. Fakultas Kedokteran > Ilmu Penyakit Dalam
Creators:
CreatorsNIM
Muhammad MiftahussururNIDN0029097909
Iswan Abbas NusiNIDN0028025003
Poernomo Boedi SetiawanNIDN8886900016
Herry PurbayuNIDN8884800016
Titong SugihartonoNIDN8836800016
Ummi MaimunahNIDN8896900016
Ulfa KholiliNIDN0004047511
Budi WidodoNIDN8804800016
Husin ThamrinNIDN8825800016
Amie VidyaniNIDN0028018002
Depositing User: arys fk
Date Deposited: 06 Dec 2019 00:46
Last Modified: 06 Dec 2019 00:46
URI: http://repository.unair.ac.id/id/eprint/92040
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