Fransisca Dita Mayangsari (2015) Uji Iritasi Kulit Sln Apms Berbasis Lipid Sistem Biner (Beeswax : Gliseril Monostearat = 50 : 50) Pada Kelinci Albino Jantan. Skripsi thesis, UNIVERSITAS AIRLANGGA.
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Abstract
This study aims at comparing the skin irritation caused by PMCA on SLN (beeswax:glyceryl monostearate = 50:50) binary system and simple cream binary system. The evaluation of the potential irritation was carried out by the Draize patch test on albino rabbits. The compositions of SLN and simple cream are p-methoxycinnamic acid 0,87 %, tween 80 10 %, propylene glycol 20 %, and acetate buffer pH 4,2 ± 0,2. PMCA-SLN was produced by high shear homogenization method and stirred at 24000 rpm for 8 minutes. While the APMS-simple cream was made by using manual technique. The skin irritation was examined based on the observation on visual change of the skin, such as erythema and edema. Based on the observation, it can be concluded that the skin irritation caused by PMCA on SLN binary system is smaller than the one caused by simple cream binary system. However, both of them are still in the same irritation category.
| Item Type: | Thesis (Skripsi) | |||||||||
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| Additional Information: | KKB KK-2 FF.F.34/15 May u | |||||||||
| Uncontrolled Keywords: | SKIN IRRITATION; PMCA-SLN LIPID BINARY SYSTEM | |||||||||
| Subjects: | Q Science > QD Chemistry > QD1-999 Chemistry S Agriculture > SF Animal culture > SF411-459 Pets > SF451-455 Rabbits and hares S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > Including veterinary genetics, ethology, anatomy, physiology, embryology, pathology |
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| Divisions: | 05. Fakultas Farmasi > Farmastika | |||||||||
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| Depositing User: | Nn Dhani Karolyn Putri | |||||||||
| Date Deposited: | 19 Feb 2016 12:00 | |||||||||
| Last Modified: | 23 Mar 2020 03:17 | |||||||||
| URI: | http://repository.unair.ac.id/id/eprint/9286 | |||||||||
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