Joseph Hartanta Purba (2019) Efek Kombinasi Metformin-Cisplatin Terhadap Derajat Viabilitas, Tingkat Apoptosis Dan Sinergitas : Studi In Vitro Pada Sel Kanker Buli. Thesis thesis, Universitas Airlangga.
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Abstract
Kanker buli merupakan kanker urogenital ketiga tersering pada pria dengan survival rate dalam 5 tahun mencapai 77%. Penelitian dilakukan untuk meningkatkan efikasi tatalaksana termasuk cisplatin sebagai regimen utama kemoterapi. Peran metformin pada tatalaksana kanker buli masih dipertanyakan.: Penelitian ini menunjukkan kombinasi metformin-cisplatin efektif menurunkan viabilitas dan menginduksi late apoptosis sel kanker urothelial. Efikasi lebih tinggi diperoleh dengan meningkatkan dosis IC-50 Metformin-cisplatin kanker buli, sinergitas, cisplatin, metformin.
Item Type: | Thesis (Thesis) | ||||||
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Additional Information: | KKA KK Tkkli 98/19 Pur e | ||||||
Uncontrolled Keywords: | Ca Buli, synergism, cisplatin, metformin | ||||||
Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) | ||||||
Divisions: | 09. Sekolah Pasca Sarjana > Ilmu Kedokteran | ||||||
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Depositing User: | Unnamed user with email indah.fatma@staf.unair.ac.id | ||||||
Date Deposited: | 13 Jan 2020 09:11 | ||||||
Last Modified: | 13 Jan 2020 09:11 | ||||||
URI: | http://repository.unair.ac.id/id/eprint/93487 | ||||||
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