Efek Kombinasi Metformin-Cisplatin Terhadap Derajat Viabilitas, Tingkat Apoptosis Dan Sinergitas : Studi In Vitro Pada Sel Kanker Buli

Joseph Hartanta Purba (2019) Efek Kombinasi Metformin-Cisplatin Terhadap Derajat Viabilitas, Tingkat Apoptosis Dan Sinergitas : Studi In Vitro Pada Sel Kanker Buli. Thesis thesis, Universitas Airlangga.

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Abstract

Kanker buli merupakan kanker urogenital ketiga tersering pada pria dengan survival rate dalam 5 tahun mencapai 77%. Penelitian dilakukan untuk meningkatkan efikasi tatalaksana termasuk cisplatin sebagai regimen utama kemoterapi. Peran metformin pada tatalaksana kanker buli masih dipertanyakan.: Penelitian ini menunjukkan kombinasi metformin-cisplatin efektif menurunkan viabilitas dan menginduksi late apoptosis sel kanker urothelial. Efikasi lebih tinggi diperoleh dengan meningkatkan dosis IC-50 Metformin-cisplatin kanker buli, sinergitas, cisplatin, metformin.

Item Type: Thesis (Thesis)
Additional Information: KKA KK Tkkli 98/19 Pur e
Uncontrolled Keywords: Ca Buli, synergism, cisplatin, metformin
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: 09. Sekolah Pasca Sarjana > Ilmu Kedokteran
Creators:
CreatorsNIM
Joseph Hartanta PurbaNIM011418196302
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorLukman HakimNIDN0009087302
Depositing User: Unnamed user with email indah.fatma@staf.unair.ac.id
Date Deposited: 13 Jan 2020 09:11
Last Modified: 13 Jan 2020 09:11
URI: http://repository.unair.ac.id/id/eprint/93487
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