Damaranie Dipahayu and Widji Soeratri and Mangestuti Agil (2014) Formulasi Krim Antioksidan Ekstrak Etanol Daun Ubi Jalar Ungu (Ipomoea batatas (L.) Lamk) Sebagai Anti Aging. Pharmaceutical Sciences and Research, 1 (3). pp. 166-179. ISSN 2407-2354

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Abstract

Purple sweet potatoes leaves (Ipomoea batatas (L.) Lamk) Antin 3 variety (IBLA) are natural antioxidant sources because of anthocyanins contents. IBLA extracted by kinetic maseration with 70 % ethanolic solution. The aims of this research are to determine antioxidant activity for DPPH (2,2-diphenyl-1-picrylhydrazil) scavenging activity and formulating IBLA extract into oil in water base cream dosage form. Both the base cream and formulation were stored at 28ºC for a period of 4 weeks to predict their stability. The evaluation parameters consisted of organoleptic, homogenity, pH value, viscosity, emulsion type, dispersive power, mechanic and freeze and thaw. Futhermore, the base cream and formulation were evaluated for their effects on skin moisture, curvature and pigmentation. The results showed that ethanolic extract of IBLA had antioxidant activity of 80.43 % compared with pure vitamin C. IC 50 value of IBLA extract is 3.68 ppm while vitamin C is 2.96 ppm. Base and antioxidant creams had a physical stability for 4 weeks. The base and antioxidant creams have no effect on promoting skin moisture. The base cream had no effect in inhibiting curvature but antioxidant cream was effective to inhibit curvature. The base showed no pigmentation inhibiting effect but antioxidant cream was effective in inhibiting pigmentation.

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