Shinta Arisanti and Gadis Meinar Sari and Paulus Liben (2014) Kombinasi Kalsitonin Salmon dan Latihan Fisik Intensitas Submaksimal Meningkatkan Ketebalan Lempeng Pertumbuhan Epifisis. In: Seminar Nasional Olahraga Kesehatan & Prestasi. Prodi S2 Ilmu Kedokteran Olahraga FK Unair, Surabaya, pp. 16-23. ISBN 978-602-71386-0-5

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Abstract

This laboratory experimental study used post test only control group design and was aimed to identify the role of salmon calcitonin administration and submaximal intensity of physical exercise on thickness of epiphyseal growth plate. Experimental animals used in this study were 6-8 weeks old growing male Rattus norvegicus rats of Strain Wistar. Those animals were divided randomly in to 4 groups and were treated as followed: 20IU/kg body weight/subcutaneous/day NaCl 0,9% to Group K0; 20IU/kg body weight/subcutaneous/day of salmon calcitonin to group 2; submaximal intensity of physical exercise to group 3 and a combination between 20IU/kg body weight/subcutaneous/day of salmon calcitonin and submaximal intensity of physical exercise to group 4. After eight weeks, thickness of epiphyseal growth plate and bone length measured. It was found that the thickness of epiphyseal growth plate increased significantly on group 2 and 4, but there was no significant result on the group 3. In conclusion, combination between short-term salmon calcitonin and submaximal intensity of physical exercise has a beneficial effect on thickness of epiphyseal growth plate.

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