Gambaran Histopatologi Hepar Mencit Jantan (Mus musculus) Yang Dipapar Asap Rokok Dan Diberi Ekstrak Etanol Kulit Pisang Kepok (Musa acuminata)

Badar Wido Utomo (2020) Gambaran Histopatologi Hepar Mencit Jantan (Mus musculus) Yang Dipapar Asap Rokok Dan Diberi Ekstrak Etanol Kulit Pisang Kepok (Musa acuminata). Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Official URL: http://www.lib.unair.ac.id

Abstract

This research aims was to proven that ethanol extract of Kepok banana peel (Musa acuminata) could reduce liver damage at the liver histopathology of male mice (Mus musculus). This research used 20 male mice (Mus musculus) 8-12 weeks old, body weight about 20 - 25 gram, with six kinds of treatment and 4 times of repetition. All the groups, except K- as a control group, was treated with cigarette smoke for 14 days. After that, P1 was treated with kepok banana peel extract 14 mg/kgBW, P2 was treated with kepok banana peel extract 28 mg/kgBW, and P3 was treated with kepok banana peel extract 56 mg/kgBW and K.O was treated with ascorbic acid 13 mg/kgBW for 14 days without cigarette smoke. Samples were scoring by Knodell (2000) and Klopfleisch (2013) method and analyzed with Kruskal Wallis and continued to Mann Whitney test. The results showed that at the group of P1 could reduce liver damage than the group of K+, K.O, P2 and P3. This showed that the ethanol extract of kepok banana peel (Musa acuminate) with a dose of 14 mg/Kg BW could reduce liver damage.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK KH 68-20 Uto g
Uncontrolled Keywords: liver, cigarette smoke, kepok banana peel, mice.
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsNIM
Badar Wido UtomoNIM061511133138
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorNove HidajatiNIDN0015116501
Thesis advisorLita Rakhma YustinasariNIDN0019068501
Depositing User: Tatik Poedjijarti
Date Deposited: 24 Jun 2020 03:54
Last Modified: 24 Jun 2020 03:54
URI: http://repository.unair.ac.id/id/eprint/95923
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