Rifatus Nadia Kristanti (2020) Pengaruh Pemberian Insulin-Like Growth Factor-1 (IGF-1) Dari Serum Kuda Crossbreed Bunting Terhadap Jumlah Sel Pulau Langerhans Pankreas Mencit (Mus musculus). Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

The purepose of the research was to determine the effect of insulin growth factor-1 (IGF-1) derived from pregnant crossbreed mare serum (PMS) on the number of islets Langerhans cells of the pancreas mice (Mus musculus). The research conducted on 35 female mice with seven treatment and five replicattes. The treatment were P0 = 0,1 ng/ml NaCl Physiological, P1, P2, P3 with respectivly 10, 20, and 40 ng/ml IGF-1 (PMS); P4, P5, and P6 with respectively 10, 20, and 40 ng/ml IGF-1 recombinant mouse, Was the number of pancreatic cells in the islets of Langerhans (Mus musculus). The data were analyzed by ANOVA test (analysis of variance). The analysis used to compare between administration of IGF-I pregnant crossbreed mare serum and IGF-I recombinant mouse The examination results showed that the administration of IGF-1 SKB gave a significant result (p< 0.05) on the number of cells on the island of Langerhans. There is a significant difference between the administration of IGF-1 SKB and recombinant IGF-1 mice on the number of mice Langerhans cells.

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