High-Calorie Diet Reduces Neuroglia Count

Nilam Anggraeni and Kristanti Wanito Wigati and Indrayuni Lukitra Wardani (2017) High-Calorie Diet Reduces Neuroglia Count. In: Proceedings of Surabaya International Physiology Seminar: SIPS. Scitepress, Surabaya, pp. 169-173. ISBN 978-989-758-340-7

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Abstract: Nowadays, high-calorie food consumption people can unwittingly affect health. Several studies have reported the effects of excesshigh-calorie food consumption can range fromhyperglycaemia to neurodegenerative interference. In the brain, astrocytes function to respond to the changing modificationof molecular brain environment.structure. This study aimed to observe the effect of a high-calorie diet on the brain histology of male mice (Mus musculus). In this study, 28 mice were randomly divided into 4 groups: the control group pre (K0); the control group post with a standard diet (K1) ;the treatment group with 0.15g of glucose diet (K2); and the treatment group with 0.25g of glucose diet (K3). Treatment was given everyday for eightweeks. Brains were then histologically processed and stained with Haematoxylin-Eosin (HE) and observation made of quantitative changes of astrocytes in the cerebral cortex. Results: Data were analyzed with Post-Hoc ANOVA. From the study, significant d ifferences were found between K0 and K2 (α <0.05). In addition, significant differences were obtained in the groups K0 and K3 (α <0.05). Meanwhile, no significant differences were found between groups (α> 0.05). In conclusion, a high-calorie diet affects thee brain histology of male mice.

Item Type: Book Section
Uncontrolled Keywords: high calorie, diet, hyperglycemia, astrocyte, cerebral cortex
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
Divisions: 01. Fakultas Kedokteran > Ilmu Faal
Nilam AnggraeniUNSPECIFIED
Kristanti Wanito WigatiNIDN0021028201
Indrayuni Lukitra WardaniNIDN0010015908
Depositing User: arys fk
Date Deposited: 12 Aug 2020 03:48
Last Modified: 12 Aug 2020 03:48
URI: http://repository.unair.ac.id/id/eprint/96822
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