Tika Ayu Nur Windasari and Lilik Maslachah and Adi Prijo Rahardjo (2016) Pengaruh Paparan Artemisinin Berulang Terhadap Diameter Pulpa Putih dan Indeks Limpa pada Mencit (Mus musculus) yang Diinfeksi Plasmodium berghei. Journal of Basic Medical Veterinary, 5 (1). pp. 8-15. ISSN 2302-6820

	Text (Jurnal) Bukti C 18 Pengaruh Paparan Artemisinin Berulang Terhadap Diameter ....pdf Download (2MB)
	Text (Peer Review) Peer review C 18 Pengaruh Paparan Artemisinin Berulang ....pdf Download (1MB)

Abstract

This study is aimed to know the effect repeated exposures artemisinin of diameter white pulp and spleen index on mice (Mus musculus) which infected by Plasmodium berghei. Forty eight mice divided into twenty mice for four control groups namely Kl, K2, K3, K4 which infected by Plasmodium berghei inthe amount of lxlOS in 0,2 ml without gave artemisinin,twenty mice for four treatment groups namely Pl, P2, P3, P4 which infected by Plasmodium berghei in the amount of lxlOS with repeated exposures artemisinin, and eight mice used as donor. The data were analyzed by univariated ANOVA using SPSS and followed with Duncan's test. The results of statistical analysis showed the size of control group'swhite pulp diameter were different from the treatment groups. While, the result of spleen index showed the difference between control groups and treatment groups, except for the fourth artemisinin exposures there was no real difference with control groups. According the study, gave repeated exposures artemisinin antimalarial reacted to white pulp diameter and spleen index on mice (Mus musculus) which infected by Plasmodium berghei, but after gave the fourth artemisinin it gave not effect to mice spleen index (lvlus musculus) which infected by Plasmodium berghei. Keywords : Artemisinin,White pulp diameter,Spleen index, Plasmodium berghei.

Actions (login required)

View Item