DNA Methylation on Bloodstain as a Forensic Age Estimation Method

Ahmad Yudianto and Masniari Novita and Muhammad Afiful Jauhani and Deka Bagus Binarsa (2020) DNA Methylation on Bloodstain as a Forensic Age Estimation Method. In: Proceedings of the International Conference on Law, Economics and Health (ICLEH 2020). Advances in Economics, Business and Management Research, 140 . Atlantis Press, Semarang, pp. 31-33. ISBN 978-94-6252-969-4

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Official URL: https://www.atlantis-press.com/proceedings/icleh-2...

Abstract

Forensic identification is an effort to help law enforcement in determining a person’s identity. Personal identity is often a problem in criminal cases, civil cases, death without identity, and mass disasters. Age estimation is very important in forensic identification. DNA methylation is a potential epigenetic modification for age estimation because DNA in aging process resembles developments that are regulated in processes that are tightly controlled by specific epigenetic modifications. In most cases of violent crime, bloodstains can be found at the crime scene. Bloodstain may come from victims, perpetrators of crime, or even from both. Bloodstain can be used to help reveal the fact scientifically Correlation between DNA methylation from bloodstain and a person’s age is unknown. The study aims to determine the correlation of DNA methylation from bloodstain and a person’s age. The study was conducted at the Institute of Tropical Disease of Universitas Airlangga from July to October 2019. The research method used was analytic observational which was conducted on 10 samples with details of 5 male and 5 female samples. The results of the study, correlation of DNA methylation with age in male subjects correlation coefficient was 0.888 with a significance value of 0.04 and in female subjects correlation coefficient was 0.834 with a significance value of 0.079. The conclusion, there is a significant correlation between percent methylation with age in male subjects, whereas in female subjects there was no significant correlation.

Item Type: Book Section
Uncontrolled Keywords: age, bloodstain, DNA methylation, estimation, forensic
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA1001-1171 Forensic medicine. Medical jurisprudence. Legal medicine
Divisions: 01. Fakultas Kedokteran > Ilmu Forensik
Creators:
CreatorsNIM
Ahmad YudiantoNIDN8888130017
Masniari NovitaUNSPECIFIED
Muhammad Afiful JauhaniUNSPECIFIED
Deka Bagus BinarsaUNSPECIFIED
Depositing User: arys fk
Date Deposited: 02 Oct 2020 02:03
Last Modified: 02 Oct 2020 02:03
URI: http://repository.unair.ac.id/id/eprint/99574
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