Muchammad Yunus, - and Endang Suprihati, - (2016) Potency of attenuated Eimeria tenella in protective immunity induction on homologous and heterologous challenges. Procedia Chemistry; Molecular and Cellular Life Sciences: Infectious Diseases, Biochemistry and Structural Biology 2015 Conference, 18. pp. 218-224. ISSN 1876-6196

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Abstract

The aim of this study was to know the protective immunity of broilers immunized with attenuated Eimeria tenella (E. tenella) on homologous and heterologous challenges. The protective immunity was represented by oocyst production and histopathological changes of cecum. The previous experiment already produced attenuated E. tenella through serial passages of precocious lines in naive chicken. Four groups of chickens were separately divided into two non-immunized control groups and two immunized with attenuated E. tenella groups, and each group was challenged with homologous and heterologous strains. The results showed significant difference in oocysts production (p<0.01) and histopathological changes between control and immunized groups. Keywords: attenuated E. tenella; protective immunity; homologous; heterologous

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