UJI IN VITRO AKTIVITAS ANTIMALARIA EKSTRAK DAUN Sauropus androgynus (L.)Merr DENGAN EKSTRAKSI BERTINGKAT TERHADAP Plasmodium falciparum

DWI FATMAWATI, 051211131174 (2016) UJI IN VITRO AKTIVITAS ANTIMALARIA EKSTRAK DAUN Sauropus androgynus (L.)Merr DENGAN EKSTRAKSI BERTINGKAT TERHADAP Plasmodium falciparum. Skripsi thesis, Universitas Airlangga.

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Abstract

The aimed of this study was to determinate antimalarial activity of nhexane extract, chloroform extract, and 96% ethanolic extract of Katuk (Sauropus androgynus (L.) Merr) leaves. In vitro test of the n-hexane, chloroform, and 96% ethanolic extract performed using 3D7 strain of Plasmodium falciparum which has been synchronized and incubated for 48 hours.The concentration of the test solution of n-hexane, chloroform, and 96% ethanolic extract were used at 100 ug/ml, 10 ug/ml, 1 ug/ml, 0.1 ug/ml, 0.01 ug/ml. The results showed that the 96% ethanolic extract of Sauropus androgynus (L.) Merr leaves have most active antimalarial activity with IC50 value of 1,917 ug/ml, and chloroform extract showed active antimalarial activity with IC50 value of 6,497 ug/ml, while n-hexane extract showed inactive antimalarial activity with IC50>100 ug / ml. Key words: Sauropus androgynus (L.) Merr, Plasmodium falciparum 3D7, antimalarial activity, in vitro

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.FT. 19-16 Fat u
Uncontrolled Keywords: Sauropus androgynus (L.) Merr, Plasmodium falciparum 3D7, antimalarial activity, in vitro
Subjects: R Medicine > RC Internal medicine > RC31-1245 Internal medicine
R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:
CreatorsNIM/NIDN
DWI FATMAWATI, 051211131174UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorWiwied Ekasari, Dr., M.SiUNSPECIFIED
ContributorRakhmawati, Dra., M.Si.UNSPECIFIED
Depositing User: Tatik Poedjijarti
Date Deposited: 02 Apr 2017 18:15
Last Modified: 02 Apr 2017 18:15
URI: http://repository.unair.ac.id/id/eprint/55649
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