STUDI PENGGUNAAN ANTIHIPERTENSI PADA PASIEN DIABETES NEFROPATI (Penelitian di Instalasi Rawat Jalan Ilmu Penyakit Dalam Rumah Sakit Universitas Airlangga Surabaya)

VENNA MAYDA PRATIWI, 051411131084 (2018) STUDI PENGGUNAAN ANTIHIPERTENSI PADA PASIEN DIABETES NEFROPATI (Penelitian di Instalasi Rawat Jalan Ilmu Penyakit Dalam Rumah Sakit Universitas Airlangga Surabaya). Skripsi thesis, Universitas Airlangga.

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Abstract

Background : Nephropathic diabetes (ND) is a common complication of diabetesmellitus. Hypertension can increase the progressivity of nephropathy. Antihypertensif therapy is aimed to reduce the progression of the nephropathy disease and preventing more complications. Aim : the aim of this study is to analyze the utilization of antihypertensive drugsin nephropathic diabetes patients. Methods : It was an observational study with retrospective data collection basedon patients‟ medical records in Outpatients Instalation in RSUA Surabaya from January 1, 2018-March 31, 2018. Results : There were 46 patients who met the inclusion criteria. Based on GFRscore, the most common classification of renal impairment in patients with diabetes in this study was on stage 4 (30.43%). The most common complications were hypertension (52.17%) and hiperlipidemia (21.74%). The drugs that often used were ARB (27.71%), CCB 27.07%, β-blockers 18.79%, diuretics loop (12.42%), ACE-I (7.96%), and potassium-sparing diuretics (6.05%). In this study, single antihypertensive use was 30.43%, two combinations antihypertensives were 31.84%, combinations three were 25.33%, combinations four were 11.57%, and combinations five were 1.44%. Drug related problem of potential drug interaction is candesartan & spironolacton 2.90%, ACE-I & ARB 2.17%. The average of blood pressure measurement that achieved therapy goal (<140/90mmHg) is 30.2%.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.FK. 31-18 Pra s
Uncontrolled Keywords: drug utilization study, nephropathic diabetes, antihypertensive drugs.
Subjects: R Medicine > RC Internal medicine > RC31-1245 Internal medicine
R Medicine > RM Therapeutics. Pharmacology > RM300-666 Drugs and their actions
Divisions: 05. Fakultas Farmasi > Farmasi Klinis
Creators:
CreatorsNIM/NIDN
VENNA MAYDA PRATIWI, 051411131084UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorBudi Suprapti, Dr., M.Si., AptUNSPECIFIED
ContributorCahyo Wibisono Nugroho, dr., Sp.PDUNSPECIFIED
ContributorMareta Rindang, S.Farm., M.Farm.Klin., Apt.UNSPECIFIED
Depositing User: Tatik Poedjijarti
Date Deposited: 18 Dec 2018 11:25
Last Modified: 18 Dec 2018 11:25
URI: http://repository.unair.ac.id/id/eprint/76942
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