PENGARUH KONSENTRASI GLUTARALDEHID TERHADAP KEKUATAN TEKAN PADA BIO SCREW BOVINE HYDROXYAPATITE-GELATIN-ALENDRONAT

OKY SAVITRI ZAINI, 051511133006 (2019) PENGARUH KONSENTRASI GLUTARALDEHID TERHADAP KEKUATAN TEKAN PADA BIO SCREW BOVINE HYDROXYAPATITE-GELATIN-ALENDRONAT. Skripsi thesis, Universitas Airlangga.

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Abstract

Background: The aim of this study was to determine the effect of glutaraldehyde addition on Bovine Hydroxyapatite-gelatine alendronate bio screw by compressive strength testing. Method: Compression strength was tested to 5 groups of bio screw formulas using the autograph instrument. Formula 1 (BHA-gel) only contains base, formula 2 (BHA-gel-alendronate) consists of a base that contains alendronate, formula 3 (BHA-gel-alendronate-GTA0,5%), formula 4 (BHA-gel-alendronate-GTA1,0%), formula 5 (BHA-gel-alendronate-GTA1,5%). There is an addition of glutaraldehyde as a cross-link agent in formula 3, formula 4, and formula 5 with different concentrations in each formula. Contentration of ale was made for 1%. Results: compressive strength analysis from the five test groups did not show a significant effects on bio screw strength (P>0.05). The test showed that the compressive strength of formula 1 (BHA-gel) and formula 2 (BHA-gel-alendronate) have greater compressive strength than formula 3 (BHA-gel-alendronate-GTA0,5%), formula 4 (BHA-gel-alendronate-GTA1,0%), and formula 5 (BHA-gel-alendronate-GTA1,5%). The compressive strength decreased when concentration of glutaraldehyde was increased. Conclusion: the addition of glutaraldehyde with 3 varians concentration (0.5%; 1%; 1.5%) did not affect the compressive strength of the bio screw which consists Bovine Hydroxyapatite (BHA)-gelatin-alendronate.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF FK 44/19 Zai p
Uncontrolled Keywords: bio screw, Bovine Hydroxyapatite (BHA), gelatin (GEL), alendronat (ALE), compressive strength, cross-link agent.
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmasi Klinis
Creators:
CreatorsNIM
OKY SAVITRI ZAINI, 051511133006UNSPECIFIED
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorDrs. Sumarno, Sp.FRS., Apt, NIDN :'0021036803UNSPECIFIED
Depositing User: Dwi Marina
Date Deposited: 20 Nov 2019 07:46
Last Modified: 20 Nov 2019 07:46
URI: http://repository.unair.ac.id/id/eprint/91272
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