Stabilitas Fisik dan Efektivitas Sediaan Tabir Surya Kombinasi Oksibenson dan Oktil Metoksisinamat dalam Basis Gel Carbomer 940 dengan Penambahan Asam Glikolat

Noorma Rosita and Tutiek Purwanti and Agustin and Noorma R (2010) Stabilitas Fisik dan Efektivitas Sediaan Tabir Surya Kombinasi Oksibenson dan Oktil Metoksisinamat dalam Basis Gel Carbomer 940 dengan Penambahan Asam Glikolat. Pharmaceutical Sciences and Research, 7 (2). pp. 16-26. ISSN 2407-2354

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Official URL: http://psr.ui.ac.id/index.php/journal/article/view...

Abstract

To fulfill the consumer expectation, cosmetic industries mostly add glycolic acid as whitening agent to the sunscreen preparation. The aim of this research was to know the effect of glycolic acid addition with the concentration of 8, 10, and 12% w/w on physical stability and effectiveness of sunscreen product containing oxybenzone and octyl methoxycinnamate (2: 7% w/w) in carbomer 940 gel. The physical stability test was done by observing physical appearance, pH, and spreading ability during 60 day storages on zone IV condition (temperature 30±0.5° and RH 70±2%). The efficacy was determinated base on SPF (Sun Protection Factor) value by spectrophotometer. The result of the physical stability test showed that glycolic acid addition affects the physical appearance (consistency) of sunscreen product, but pH and spreading ability are relatively stable. The efficacy test result showed that the addition of glycolic acid has an effect on SPF value of sunscreen product. Product which combined with glycolic acid showed a significant increase of SPF value, compared to control formula. The addition of glycolic acid increased SPF value and alter the effectiveness category from extra protection to maximal protection.

Item Type: Article
Uncontrolled Keywords: glycolic acid, oxybenzone, octyl methoxycinnamate, SPF, sunscreen
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi
Creators:
CreatorsNIM
Noorma RositaNIDN0025126506
Tutiek PurwantiNIDN0010025705
AgustinUNSPECIFIED
Noorma RUNSPECIFIED
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 04 Mar 2021 06:17
Last Modified: 04 Mar 2021 06:17
URI: http://repository.unair.ac.id/id/eprint/104296
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