Nailul Ngizzah (2020) Potensi Ekstrak Etanol Daun Kelor (Moringa oleifera) Terhadap Jumlah Sel Spermatogenik Dan Sel Leydig Tikus Putih (Rattus norvegicus) Yang Diinduksi Gentamisin. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

The purpose of this study was to determine the administration of ethanolextract of moringa leaves can improve the number of cells of the spermatogenic and Leydig cells of white rats induced gentamicin. This study used 25 white rats males which were divided in five treatment groups in a complete random. For 14 days, rats were given gentamicin 5 mg/kg BW/day subcutaneously except for the group of K-. After the 14 days given gentamicin, rats were administered moringa leaf extract for 14 days by medication except for the group of K- and K+. The groups K - and K+ given CMC-Na 0.5% to as much as 0.5 ml. Group P1 was given the extract of leaves of moringa 200 mg/kg BW/day. Group P2 was given the extract of leaves of moringa 316 mg/kg BW/day. The group P3 was given moringa leaf extract 500 mg/kg BW/day. The results of data analysis with test Oneway ANOVA shows the difference in the number of cells of the spermatogenic and Leydig cells. Based on the results of Duncan's test or Tukey test shows the differences in each group. Based on the research conducted it can be concluded that the administration of moringa leaf extract orally in male rats induced by gentamicin affect the number of cells of the spermatogenic and Leydig cells. The optimal dosage of moringa leaf extract used in this study is 316 mg/kg BW/ day.

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