Mulyadi Tanjung and Tjitjik Srie Tjahjandarie and Ratih Dewi Saputri and Baharrani Dwi Kurnia and Muhammad Faisal Rachman and Yana Maolana Syah (2019) Calotetrapterins A-C, three new pyranoxanthones and their cytotoxicity from the stem bark of Calophyllum tetrapterum Miq. Natural Product Research, 35 (3). pp. 1-6. ISSN 1478-6419 (Print) 1478-6427 (Online)
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Abstract
Three new pyranoxanthones, calotetrapterins A-C (1-3) were isolated from the stem bark of Calophyllum tetrapterum Miq along with three known xanthones, α-mangostin (4), garciniafuran (5), and pyranojacareubin (6). All structures were elucidated based on their IR, UV, HRESIMS, 1 D (1H, 13C) and 2 D (HMBC, HMQC) NMR spectral data. Compounds 1-6 were tested to P-388 cells for cytotoxic activity, compound 2 exhibited high activity with IC50 value 1.0 μM. (Graphical abstract)
Item Type: | Article | ||||||||||||||
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Uncontrolled Keywords: | Calotetrapterins A-C,pyranoxanthone, Calophyllum, tetrapterum, P-388 cell | ||||||||||||||
Subjects: | Q Science Q Science > QD Chemistry |
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Divisions: | 08. Fakultas Sains dan Teknologi > Kimia | ||||||||||||||
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Depositing User: | Mr Vega Andi Budiman | ||||||||||||||
Date Deposited: | 19 Apr 2021 03:40 | ||||||||||||||
Last Modified: | 19 Apr 2021 03:40 | ||||||||||||||
URI: | http://repository.unair.ac.id/id/eprint/105806 | ||||||||||||||
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