Calotetrapterins A-C, three new pyranoxanthones and their cytotoxicity from the stem bark of Calophyllum tetrapterum Miq

Mulyadi Tanjung and Tjitjik Srie Tjahjandarie and Ratih Dewi Saputri and Baharrani Dwi Kurnia and Muhammad Faisal Rachman and Yana Maolana Syah (2019) Calotetrapterins A-C, three new pyranoxanthones and their cytotoxicity from the stem bark of Calophyllum tetrapterum Miq. Natural Product Research, 35 (3). pp. 1-6. ISSN 1478-6419 (Print) 1478-6427 (Online)

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Official URL: https://www.tandfonline.com/doi/abs/10.1080/147864...

Abstract

Three new pyranoxanthones, calotetrapterins A-C (1-3) were isolated from the stem bark of Calophyllum tetrapterum Miq along with three known xanthones, α-mangostin (4), garciniafuran (5), and pyranojacareubin (6). All structures were elucidated based on their IR, UV, HRESIMS, 1 D (1H, 13C) and 2 D (HMBC, HMQC) NMR spectral data. Compounds 1-6 were tested to P-388 cells for cytotoxic activity, compound 2 exhibited high activity with IC50 value 1.0 μM. (Graphical abstract)

Item Type: Article
Uncontrolled Keywords: Calotetrapterins A-C,pyranoxanthone, Calophyllum, tetrapterum, P-388 cell
Subjects: Q Science
Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsNIM
Mulyadi TanjungNIDN0022046503
Tjitjik Srie TjahjandarieNIDN0006026502
Ratih Dewi SaputriUNSPECIFIED
Baharrani Dwi KurniaUNSPECIFIED
Muhammad Faisal RachmanUNSPECIFIED
Yana Maolana SyahUNSPECIFIED
Depositing User: Mr Vega Andi Budiman
Date Deposited: 19 Apr 2021 03:40
Last Modified: 19 Apr 2021 03:40
URI: http://repository.unair.ac.id/id/eprint/105806
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