Mulyadi Tanjung and Tjitjik Srie Tjahjandarie and Ratih Dewi Saputri and Andre Harsono and Muhammad Fajar Aldin (2020) A New Cinnamyl Acid Derivative from the Roots of Willughbeia coriacea Wall. Natural Product Sciences, 26 (1). pp. 79-82. ISSN 1226-3907(pISSN) / 2288-9027(eISSN)

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Abstract

A new cinnamyl acid derivative, willughbein A (1) along with pinoresinol (2), alyterinate A (3), and scopoletin (4), were isolated from the roots of Willughbeia coriacea Wall. The structure of 1 has been determined based on HRESIMS, 1D, and 2D NMR spectral data. All of the isolates were evaluated for their cytotoxicity against three human cancer cells (HeLa, T47D, MCF-7, and P-388). Compound 3 showed moderate activity against P-388 cells with an IC50 value of 3.04 ㎍/mL.

Item Type:	Article
Uncontrolled Keywords:	Willughbein A, Cinnamyl acid, Willughbeia coriacea, Cytotoxic
Subjects:	Q Science > Q Science (General) Q Science > QD Chemistry
Divisions:	08. Fakultas Sains dan Teknologi > Kimia
Creators:	Creators NIM Mulyadi Tanjung NIDN0022046503 Tjitjik Srie Tjahjandarie NIDN0006026502 Ratih Dewi Saputri UNSPECIFIED Andre Harsono UNSPECIFIED Muhammad Fajar Aldin UNSPECIFIED
Depositing User:	Mr Vega Andi Budiman
Date Deposited:	19 Apr 2021 03:58
Last Modified:	19 Apr 2021 03:58
URI:	http://repository.unair.ac.id/id/eprint/105810
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