Kusdwijono, - and Vita Dwi Wijayanti, - and Retno Asih Setyoningrum, - and Landia Setiawati, - (2010) Risk Factors of Tuberculosis Infection in Children with Tuberculosis Contact. In: Paediatrica Indonesiana. Indonesian Pediatric Society, Surabaya, pp. 1-8. ISBN 0030-9311

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Abstract

Background: Household contact with acid fast bacilli positive adult is the key of tuberculous (TB) transminission. It also influence by agent, host, and environmental factors that may increase risk for TB infection in children. Objective: To evaluate risk factors of tuberculosis infection in children contact with infectious tuberculosis cases. Methods: A cross-sectional study of children at Pediatric Outpatient Clinic, dr. Soetomo hospital was done. Tuberculosis infection was confirmed by positive tuberculin skin test using PPD RT 23 2 Tubercullin Unit. The variable of risk factors were age, BCG immunization, nutritional status, high density of people, bacterial load (index case), air sanitation, smoke exposure and sleep in the same room, which were analyzed by multivariate logistic regression. Results: There were 15 infection of tuberculosis from 29 children with household contact. 12 were male with median age were 5 years (range 1-14 yeras). The smoke exposure (OR: 35.51; 95% Cl: 1.46-858.72), age (OR: 14.89; 95% Cl:0.66-335.11), and nutritional status (OR; 7.79; 95% Cl: 0.53-113.74) were risk factors for tuberculous infection in this population. The smoke exposure was the most significant risk factor. Conclusion: The smoke exposure is the most significant risk factor for tuberculosis infection in this population.

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