Nurullia Tanjung (2020) Uji Aktivitas Ekstrak Daun Sida rhombifolia L. Sebagai Antivirus Hepatitis C. Skripsi thesis, UNIVERSITAS AIRLANGGA.
![[img]](https://repository.unair.ac.id/style/images/fileicons/text.png) |
Text
1. HALAMAN JUDUL.pdf Download (857kB) |
|
Text
2. ABSTRACT .pdf Download (245kB) |
|
Text
3. DAFTAR ISI .pdf Download (462kB) |
|
Text
4. BAB I PENDAHULUAN .pdf Download (384kB) |
|
Text
5. BAB II TINJAUAN PUSTAKA.pdf Restricted to Registered users only until 6 September 2024. Download (1MB) | Request a copy |
|
Text
6. BAB III KERANGKA KONSEPTUAL.pdf Restricted to Registered users only until 6 September 2024. Download (382kB) | Request a copy |
|
Text
7. BAB IV METODE PENELITIAN.pdf Restricted to Registered users only until 6 September 2024. Download (622kB) | Request a copy |
|
Text
8. BAB V HASIL PENELITIAN DAN PEMBAHASAN.pdf Restricted to Registered users only until 6 September 2024. Download (523kB) | Request a copy |
|
Text
9. BAB VI KESIMPULAN DAN SARAN.pdf Restricted to Registered users only until 6 September 2024. Download (239kB) | Request a copy |
|
Text
10. DAFTAR PUSTAKA.pdf Download (405kB) |
|
Text
11. LAMPIRAN.pdf Restricted to Registered users only until 6 September 2024. Download (2MB) | Request a copy |
|
Text
FF.FT.21-21-Surat Embargo.pdf Download (235kB) |
Abstract
Sida rhombifolia L. is a plant of the Malvaceae family which has been used as a traditional medicine for curing jaundice. Previous research reported that S. rhombifolia L. seed extract possessed hepatoprotective. This study aimed to determine the antiviral activity of S. rhombifolia against hepatitis C virus. In vitro anti-viral activity was conducted to ethanol, n-hexane, dichloromethane, and methanol extracts of S. rhombifolia L. leaves. Various concentrations of extracts were inoculated onto the Huh7it infected cells. Cytotoxicity analysis was evaluated by MTT (3-[4,5-dimethylthiazol-2-yl]- 5-[3carboxymethoxyphenyl]-2-[4-sulfophenyl]-2H-tetrazolium) assay. The result was obtained that extracts of ethanol, n-hexane, dichloromethane, and methanol of S. rhombifolia L. possessed strong activity against HCV with IC50 value of 2.0 ± 0.6 µg/ml; 1.5 ± 0.2 µg/ml; 0.5 ± 0.1 µg/ml; 0.8 ± 0.8 µg/ml, respectively. The cytotoxicity test showed no toxic effect with CC50 value of ethanol extract was 387,9 ± 8,6 µg/ml. Those results suggest that ethanol extract, n-hexane, dichloromethane, and methanol of S. rhombifolia L. leaves are active as anti-hepatitis C virus.
| Item Type: | Thesis (Skripsi) | ||||||
|---|---|---|---|---|---|---|---|
| Additional Information: | KKC KK FF.FT 21/21 Tan u | ||||||
| Uncontrolled Keywords: | Sida rhombifolia L., hepatitis C virus, cell culture | ||||||
| Subjects: | R Medicine > R Medicine (General) > R735-854 Medical education. Medical schools. Research | ||||||
| Divisions: | 05. Fakultas Farmasi > Farmakognosi Fitokimia | ||||||
| Creators: |
|
||||||
| Contributors: |
|
||||||
| Depositing User: | Andri Yanti | ||||||
| Date Deposited: | 06 Sep 2021 07:29 | ||||||
| Last Modified: | 06 Sep 2021 07:29 | ||||||
| URI: | http://repository.unair.ac.id/id/eprint/110058 | ||||||
| Sosial Share: | |||||||
Actions (login required)
 |
View Item |