Sukardiman, - and Noor Cholies Zaini, - and Aty Widyawaruyanti, - and Sismindari, - and Rice Disi Oktarina, - (2009) Pinostrobin Isolate from Kaempferia Pandurata Roxb Induced Apoptosis in TD-47 Human Breast Cancer Cell Line. Laporan Penelitian. UNIVERSITAS AIRLANGGA, Surabaya.
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Text (LAPORAN PENELITIAN)
KKB LP.218-10 Pin.pdf Download (2MB) |
Abstract
Pinostrobin isolated from Koempferia pandurato Roxb which belongs to the family of Zingiberaceae, was observed to induce apoptosis in TD-47 human breast cancer cell line. Pinostrobin at 10 , 50 ,100 ug/ml for 24, 48 and 72 h induced DNA fragmentation and Increased the percentage of apoptotic cell after acridine orange - ethidium brornide staining. Our result demonstrated that andrographolide can induce apoptosis in in TD-47 human breast cancer cell line in a time and concentration dependent manner by increase expression of p53 , bax , caspase-3 and decreased expression of bc1-2 by immunohistochemical analysis.
| Item Type: | Monograph (Laporan Penelitian) | ||||||||||||
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| Additional Information: | KKB LP.218-10 Pin | ||||||||||||
| Uncontrolled Keywords: | Pinostrobin, Kaempferia pondurata Roxb , TD-47 cell , Apoptosis, p53 | ||||||||||||
| Subjects: | R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica | ||||||||||||
| Divisions: | 05. Fakultas Farmasi > Ilmu Kefarmasian | ||||||||||||
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| Depositing User: | S.Sos. Sukma Kartikasari | ||||||||||||
| Date Deposited: | 20 Apr 2022 02:28 | ||||||||||||
| Last Modified: | 20 Apr 2022 02:28 | ||||||||||||
| URI: | http://repository.unair.ac.id/id/eprint/115619 | ||||||||||||
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