Meliana, Resti Yudhawati and Guntur, Megawati RN. (2021) Biological Therapy for Asthma. Jurnal Respirasi, 7 (1). ISSN 2407-0831

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Abstract

Asthma is a heterogeneous chronic inflammatory disease in the respiratory tract that leads to recurrent episodic symptoms. Study about the mechanism of pathophysiology and immunology which stimulates chronic inflammation in asthma has been greatly developed. The understanding of inflammation mediator that is predominant on various asthma phenotypes could be useful for development of diagnosis and targeted therapy. Standard asthma therapy administered through the airway has limited effects only in the airway. The knowledge of molecular pathophysiology and immunology of this disease developed interest of the drugs that perform proximally from inflammation process in the airway, in this case is biological therapy. Several biological therapies have been investigated for its efficacy on human, including Anti IgE (Omalizumab), Anti Interleukin-5 (Mepolizumab, Reslizumab, Benralizumab), Anti Interleukin-4/Interleukin-13 (Dupilumab), and Anti Interleukin-17 (Secukinumab and Brodalumab).

Item Type:	Article
Subjects:	R Medicine > R Medicine (General) R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions:	01. Fakultas Kedokteran > Ilmu Pulmonologi dan Ilmu kedokteran Respirasi
Creators:	Creators NIM Meliana, Resti Yudhawati NIDN 0006127605 Guntur, Megawati RN. UNSPECIFIED
Depositing User:	arys fk
Date Deposited:	04 Nov 2022 01:04
Last Modified:	03 Apr 2023 06:46
URI:	http://repository.unair.ac.id/id/eprint/118466
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