Immune Response to Burn Injury: Hyperinflammation and Immunosuppression

SEPTIN MAULUDIYANA, SEPTIN and Aryati, Aryati and Yoes Prijatna Dachlan, Yoes and Iswinarno Doso Saputro, Iswinarno and Muhaimin Rifa’i, Muhaimin (2021) Immune Response to Burn Injury: Hyperinflammation and Immunosuppression. Indian Journal of Forensic Medicine and Toxicology, 15 (3). ISSN 0973-9122

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Abstract

Abstract Burn is an injury to the skin or other tissue. Mostly, it caused by contacting with hot liquids, solids, and flames. The important thing that should be consider in burn incident is the severity of burn and it based on the depth and area of the burn injury. The severity of burns will cause differences of pathophysiological responses. This was a literature review study. Various articles were collected from online database including reports, journals, and published in the last 10 years. The articles were from the scholar journals. The systemic inflammatory response in severe level of burns was not given good response to disappear of lesion burn and initiating tissue repair. Moreover, it was given an organ failure to the patient. The body responded to this incident by releasing antiinflammatory mediators. This response is very strong and prolonged, so it caused immunosuppression and increase the risk of secondary infection to the patients. Burns affects the patient’s immune system. The ratio between pro and antiinflammatory mediators are determining the patient’s subsequent status.

Item Type: Article
Subjects: R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions: 01. Fakultas Kedokteran > Bedah Plastik Rekonstruksi dan Estetik (Spesialis)
Creators:
CreatorsNIM
SEPTIN MAULUDIYANA, SEPTIN091514353004
Aryati, AryatiNIDN0015086304
Yoes Prijatna Dachlan, YoesUNSPECIFIED
Iswinarno Doso Saputro, IswinarnoNIDK: 8839700016
Muhaimin Rifa’i, MuhaiminUNSPECIFIED
Depositing User: arys fk
Date Deposited: 02 Jan 2023 13:42
Last Modified: 02 Jan 2023 13:42
URI: http://repository.unair.ac.id/id/eprint/119390
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