Yunias Setiawati, Yunias and H.J. Mukono, Mukono and Joni Wahyuhadi, Joni and Endang Warsiki, Endang and Sasanti Yuniar, Sasanti Is there an Effect of Serotonin on Attention Deficit Hyperactivity Disorder. Indian Journal of Public Health Research & Development, 11 (1). ISSN 0976-5506

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Abstract

AbstractBackground: Attention decit hyperactivity disorder (ADHD) is a neurobiological disorder with a prevalence of 5%-10% in the world that negatively impacts school behavior and achievement. There have been many studies reveals that attention disorders are caused by the decreased levels of dopamine and norepinephrine neurotransmitter. However, particular concern nowadays are the emotional and behavioral problems. The emotional and behavioral problem is suspected to be caused by the decrease in serotonin level. The aim of this study was to determine the dierence in serotonin level between ADHD and non-ADHD children.Method: This study was an observational case-control study design using random sampling method. Subject of this study was children in Bina Karya Elementary School Surabaya. ADHD severity was assessed using Conners Abreviated Rating Scale. Examination of serotonin levels in blood was done by ELISA method. Informed consent was signed by parents before the study. Data was analyzed using independent T-test.Results: 44 (23 ADHD and 21 non-ADHD) children from grade 1 to 6 was included in the study. Based on the gender, 13 children were girls and 31 children were boys. Serotonin level in ADHD children was signicantly higher than non-ADHD children (2.148 ± 0.94 vs 2.006 ± 0.115 μmol/L; p = 0.0001).Conclusion: Serotonin level in ADHD children was signicantly higher than non-ADHD children

Item Type:	Article
Subjects:	R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions:	01. Fakultas Kedokteran > Ilmu Bedah Saraf
Creators:	Creators NIM Yunias Setiawati, Yunias NIDN8837800016 H.J. Mukono, Mukono UNSPECIFIED Joni Wahyuhadi, Joni NIDN8885900016 Endang Warsiki, Endang NIDN8829940017 Sasanti Yuniar, Sasanti NIDN8876800016
Depositing User:	arys fk
Date Deposited:	20 Feb 2023 22:52
Last Modified:	10 Apr 2023 04:48
URI:	http://repository.unair.ac.id/id/eprint/120049
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