Dwi Yuli Pujiastuti, .- and Muhamad Nur Ghoyatul Amin, .- and Mochammad Amin Alamsjah, .- and Jue-Liang Hsu, .- (2019) Marine Organisms as Potential Sources of Bioactive Peptides that Inhibit the Activity of Angiotensin I-Converting Enzyme: A Review. Journal Molecules, 24 (14). pp. 1-16. ISSN 14203049

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Abstract

Angiotensin I-converting enzyme (ACE) is a paramount therapeutic target to treat hypertension. ACE inhibitory peptides derived from food protein sources are regarded as safer alternatives to synthetic antihypertensive drugs for treating hypertension. Recently, marine organisms have started being pursued as sources of potential ACE inhibitory peptides. Marine organisms such as fish, shellfish, seaweed, microalgae, molluscs, crustaceans, and cephalopods are rich sources of bioactive compounds because of their high-value metabolites with specific activities and promising health benefits. This review aims to summarize the studies on peptides from di�erent marine organisms and focus on the potential ability of these peptides to inhibit ACE activity.

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