R. Darmawan Setijanto (1999) Kadar Amonia Sal Iva Istirahat Sebagai Pemicu Pembentukan Karang Gigi Supragingiva. Disertasi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Ammonia is one of saliva organic components wich can increase the pH of whole-resting saliva. This pH condition leads to supragingival calculus formation. Previous studies on supragingival calculus formation focused separately and only on the deterrnifl..ation of its direct cause and the cause of whole-resting saliva pH increase. These previous studies shown that whole-resting saliva played an important role. However, mechanism due to ammonia role has -not been known yet. Thus such study resulted in lack of description on supraginggival calculus formation. Therefore, a study on integrated mechanism of has been carried out on complete mechanism of supragingival calculus formation in vivo was carried out. This study was conducted by using a longitudinal-analytical observation method. Population was patients of SDAU Periodontics clinic, with and without dental calculus, aged between 18 and 25. Simple Random Sampling was taken. Unit of analysis wich consisted of 35 whole-resting saliva samples was taken at 09:00 a.m. after fasting. It observed concentration of ammonia, bicarbonate, total calcium, total phosphate, total lipid and pH Detellilination of supragingival calculus formation was observed at the beginning of the study (after their calculus cleansing), after 4, 8 and 18 weeks. Regression Analysis showed that ammonia was the main contributor to wholeresting saliva pH, whereas whole-resting saliva pH was the main contributor to supragingival calculus formation. Path analysis confirmed that ammonia was the trigger of supragingivar calculus formation trough its contribution to whole-resting saliva pH. The proven hypotesis of this study pointed out that, in the concept of supraginggival calculus formation, there was a difference between concept proven in vitro and the new one proven in vivo. This study has found a new theoretical concept in supraginggival calculus formation in vivo.

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