Leonard Christiaan Nelwan,, - and Sindy Cornelia Nelwan, - and Asti Meizarini, - and Nunthawan Nowwarote, - (2022) The Role of Static Magnetic Healing Abutment in Osteoblastic Differentiation to Reduce Marginal Crestal Bone Loss. Journal of International Dental and Medical Research, 15 (2). ISSN 1309-100X

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Abstract

Dental implantation successfully can be made if the implant, bone, and soft tissue are integrated to increase patient satisfaction. Marginal crestal bone loss, if once occurring, will directly affect the longevity of dental implants; thus, it causes implant failure. Static magnetic field (SMF) has always been a great interest in dentistry as it has been used for various purposes in prosthodontics including prosthesis and overdentures. The use of SMF as healing abutment is under investigation. This study investigated how SMF can reduce marginal crestal bone loss after dental implant placement. Functioning the static magnetic field (SMF), canonical Wnt ligands can be upregulated, and phosphorylation of GSK-3b and total b-catenin expression in osteoblasts are promptly stimulated. SMF activated the Wnt/b-catenin signaling pathway to invigorate the osteoblastic differentiation. SMF-activated Wnt-Fzd-LRP5/6 binding events can accumulate β-catenin intracellularly and phosphorylate GSK3, which activates MAPK and NF-κb for osteoblastogenic gene and Runx2 transcription. Therefore, SMFs positively affect bone healing and periodontal regeneration. Static magnetic healing abutment plays a role in increasing osteoblastic differentiation; hence, it reduces marginal crestal bone loss. Review (J Int Dent Med Res 2022; 15(2): 896-898

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