Ira Arundina, - and Indeswati Diyatri, - and Tuti Kusumaningsih, - and Meircurius Dwi Condro Surboyo, - and Elita Monica, - and Novitasari Mira Afanda, - (2021) The Role of Rice Hull Liquid Smoke in the Traumatic Ulcer Healing. European Journal of Dentistry, 15 (1). pp. 33-38. ISSN 13057456, 13057464

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Abstract

Objective The aim of this study was to prove the role of rice hull liquid smoke (RH-LS) on lymphocytes, macrophages, fibroblasts, interleukin 6 (IL-6), and transforming growth factor β (TGF-β) expression during traumatic ulcer healing. Materials and Methods The RH-LS was obtained from the pyrolysis process. Traumatic ulcers were made 10 mm along the labial fornix incisive inferior of Wistar rat using a round stainless-steel blade. In control group, traumatic ulcers were treated using sterile water, and meanwhile in experimental group were treated using RH-LS once a day for 3, 5, and 7 days. After treatment, animal was terminated and their labial fornix incisive inferior tissues were biopsy and stained using hematoxylin and eosin staining to determine lymphocytes, macrophages, and fibroblasts. The IL-6 and TGF-β expressions were analyzed used immunohistochemistry staining. Result The lymphocytes, macrophages, and fibroblasts were higher in the RH-LS group for 3-, 5-, and 7-day treatment (p < 0.05). The IL-6 expression was higher only in the 5-day treatment, and the TGF-β expression was higher in the 3- and 7-day treatment. Conclusion The RH-LS able to accelerated the traumatic ulcer healing by increasing the number of lymphocytes, macrophages, fibroblasts, IL-6, and TGF-β expression.

Item Type:	Article
Subjects:	R Medicine R Medicine > RK Dentistry
Divisions:	02. Fakultas Kedokteran Gigi > Oral Biology
Creators:	Creators NIM Ira Arundina, - NIDN0028107102 Indeswati Diyatri, - NIDN0015036204 Tuti Kusumaningsih, - NIDN0023105202 Meircurius Dwi Condro Surboyo, - NIDN0030059010 Elita Monica, - - Novitasari Mira Afanda, - -
Depositing User:	Rudy Febiyanto
Date Deposited:	16 Apr 2023 03:23
Last Modified:	16 Apr 2023 03:23
URI:	http://repository.unair.ac.id/id/eprint/123593
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