Afif Nurul Hidayati, Afif and Citra Dwi Harningtyas, Citra and Damayanti, Damayanti and Maylita Sari, Maylita and Linda Astari, Linda and Diah Mira Indramaya, Diah and M. Yulianto Listiawan, - and Budi Utomo, Budi and Budiono, Budiono and Dwi Murtiastutik, Dwi and Septiana Widyantari, Septiana and Astindari, Astindari Mucocutaneous Manifestations in HIV/AIDS Patients. Berkala Ilmu Kesehatan Kulit dan Kelamin, 33 (3). ISSN eISSN : 25494082 | pISSN : 25494082

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Abstract

Background: The main target of human immunodeficiency virus (HIV) is cluster of differentiation 4 (CD4) T lymphocytes and several other immune cells that have CD4 receptors. They are also present in skin and mucosa, such as Langerhans cells (LC). Mucocutaneous lesions are one of the first clinical presentations of immunosuppression in HIV seropositive patients that manifest at different stages of the infection and require early diagnosis and prompt treatment. Purpose: To determine the clinical characteristics and the pattern of various mucocutaneous manifestations in Human immunodeficiency virus/Acquired immune deficiency syndrome (HIV/AIDS) patients at Intermediate Care and Infectious Diseases Dr. Soetomo General Academic Hospital Surabaya. Methods: This is a descriptive retrospective study with a cross-sectional design. The study subject was classified as all HIV-AIDS patients with mucocutaneous manifestations treated in Intermediate Care and Infectious Diseases Dr. Soetomo General Academic Hospital Surabaya in 2019. Result: Out of the 614 patients who participated in the study, 72.1% were males. The majority of patients were in the age group 25–49 years (75.4%). The most common risk factor was heterosexuality (41.7%). Based on the distribution of mucocutaneous manifestations, the most common mucocutaneous manifestation was candidiasis mucocutan 387 patients (49.4%) followed by the pruritic papular eruption (PPE) 118 patients (15.1%) and human papillomavirus infection 57 patients (7.3%). Conclusion: Mucocutaneous manifestations occur throughout the course of HIV infection, and they can be considered as good clinical indicators for the progression of the disease and underlying immune status in resource-poor settings.

Item Type:	Article
Subjects:	R Medicine > R Medicine (General) > R5-920 Medicine (General)
Divisions:	01. Fakultas Kedokteran > Ilmu Kesehatan Kulit dan Kelamin (Spesialis)
Creators:	Creators NIM Afif Nurul Hidayati, Afif NIDN8855610016 Citra Dwi Harningtyas, Citra UNSPECIFIED Damayanti, Damayanti UNSPECIFIED Maylita Sari, Maylita UNSPECIFIED Linda Astari, Linda UNSPECIFIED Diah Mira Indramaya, Diah NIDN8898700016 M. Yulianto Listiawan, - NIDN8806800016 Budi Utomo, Budi NIDN0018055904 Budiono, Budiono NIDN0003046406 Dwi Murtiastutik, Dwi NIDN8860010016 Septiana Widyantari, Septiana UNSPECIFIED Astindari, Astindari UNSPECIFIED
Depositing User:	arys fk
Date Deposited:	28 Apr 2023 06:40
Last Modified:	12 Oct 2023 02:28
URI:	http://repository.unair.ac.id/id/eprint/125317
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