Nguyen Hoang Uyen, - and Retno Widyowati, - and Melanny Ika Sulistyowaty, - and Sachiko Sugimoto, - and Yoshi Yamano, - and Susumu Kawakami, - and Hideaki Otsuka, - and Katsuyoshi Matsunami, - (2020) Firmosides A and B: two new sucrose ferulates from the aerial parts of Silene firma and evaluation of radical scavenging activities. Journal of Natural Medicines, 74 (4). pp. 796-803. ISSN 1340-3443

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Abstract

Two new tri-ferulates of sucrose, firmosides A and B (1 and 2, respectively), together with 18 known compounds (3–20), were isolated from the aerial parts of Silene firma. The structures of the isolated compounds were elucidated by various spectroscopic methods, including 1D, 2D NMR, and high-resolution electro-spray ionization–mass spectrometry (HR-ESI–MS). All the isolated compounds were evaluated for their free radical scavenging activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. As a result, two new compounds (1, 2) and 11 demonstrated significant radical scavenging activity, implying the usefulness as antioxidant agents.

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