Deborah Melati, - and Martono Tri Utomo, - and Mahendra Tri Arif, - and Risa Etika, - and Dwiyanti Puspitasari, - and Talitha Aden, - Outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and multidrug-resistant Acinetobacter baumannii in the neonatal intensive care unit, Dr Soetomo General Hospital, Indonesia: A case series. Deborah Melati,. Sri Lanka Journal of Child Health 2022, 51 (2). pp. 294-298. ISSN 2386110X-13915452

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Abstract

Abstract Nosocomial infection outbreaks occur more frequently in premature infants in the Neonatal Intensive Care Unit (NICU). Commonly caused by extended-spectrum beta-lactamase (ESBL) producing Klebsiella pneumoniae and multidrug- resistance (MDR) Acinetobacter baumannii strains. This report describes the outbreak and intervention to eliminate it. We reported 6 neonates at NICU concurrently developed sepsis. Three cases were caused by ESBL producing Klebsiella pneumonia strains susceptible to levofloxacin and trimethoprim- sulfamethoxazole. Other to MDR Acinetobacter baumannii susceptible to cefoperazone sulbactam. The outbreak caused mortality in five cases (case fatality rate 75%). We describe the control measure from the NICU outbreak to interrupt chain of transmission and hospital policies adopted.

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