Lita Diah Rahmawati, - and Joewono Soeroso, - and Aryati, - (2022) The roles of Single Nucleotide Polymorphism (SNP) Endoplasmic Reticulum Aminopeptidase 1 (ERAP 1) gene in axial spondyloarthritis Indonesian adults. Annals of Medicine and Surgery, 77 (-). -.
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Abstract
This study comprised of two phases including a cross sectional study and an in-vitro experiment in post-test with a control-group design. Participants underwent a PCR investigation searching for HLA-B27. Disease activities were measured by Ankylosing Spondylitis Disease Activity Score-Erythrocyte Sedimentation Rate (ASDAS-ESR) and modified Stokes Ankylosing Spondylitis Spinal Score (mSASSS). Subjects with HLA-B27 positive underwent PCR ERAP1 gene rs27434, genome-sequencing, and analysis. ELISA sandwich method was used to measure ERAP-1, IL-17, and IL-23 levels with lipopolysaccharide and IFN-γ induction. Analysis using independent t-test, Mann Whitney, and Pearson correlation test with p < 0.05
| Item Type: | Article | ||||||||
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| Uncontrolled Keywords: | ASDAS-ESR Axial spondyloarthritis ERAP1 mSASSS Interleukin | ||||||||
| Subjects: | R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA1190-1270 Toxicology. Poisons | ||||||||
| Divisions: | 01. Fakultas Kedokteran > Parasitologi | ||||||||
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| Depositing User: | Unnamed user with email indah.fatma@staf.unair.ac.id | ||||||||
| Date Deposited: | 09 Jun 2023 04:30 | ||||||||
| Last Modified: | 09 Jun 2023 04:30 | ||||||||
| URI: | http://repository.unair.ac.id/id/eprint/127086 | ||||||||
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