Osteogenesis Imperfecta: An Overview

Rahma Ira Mustikasari, - and Nur Rochmah, - and Muhammad Faizi, - and Qurrota Ayuni Novia Putri, - (2022) Osteogenesis Imperfecta: An Overview. International Journal of Scientific Advances, 3 (3). pp. 351-357. ISSN 2708-7972

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Official URL: https://www.ijscia.com/?p=9572

Abstract

Osteogenesis Imperfecta (OI) or commonly referred to as brittle bone disease is a congenital connective tissue formation disorder characterized by bone fragility, osteopenia, skin disorders, blue sclera, dentinogenesis imperfecta (DI), and hearing loss. The diagnosis of Osteogenesis Imperfecta is based on history, clinical examination, lumbar bone density, bone biochemistry and radiographic findings. Diagnosis of osteogenesis imperfecta can be difficult and some primary skeletal disorders can be mixed with osteogenesis imperfecta. Management of OI requires a multidisciplinary approach such as endocrinologists, pediatricians, orthopedic surgeons, dentists, medical rehabilitation specialists, geneticists, psychologists, and occupational therapists. Bisphosphonate therapy has been shown to be effective in reducing pain, fracture frequency, and disability. Medical services such as bisphosphonate treatment and rehabilitation in individuals with OI have the long-term goal of optimizing the health and well-being of bone fragility and deformity.

Item Type: Article
Uncontrolled Keywords: Osteogenesis Imperfecta (OI), multidisciplinary approach, bisphosphonate therapy
Subjects: R Medicine > R Medicine (General)
R Medicine > RJ Pediatrics
Divisions: 01. Fakultas Kedokteran > Ilmu Kesehatan Anak (Sub Spesialis)
Creators:
CreatorsNIM
Rahma Ira Mustikasari, -UNSPECIFIED
Nur Rochmah, -NIDN0029047909
Muhammad Faizi, -NIDN8890900016
Qurrota Ayuni Novia Putri, -NIM011411131047
Depositing User: Mrs Elok Dian Nuraeni
Date Deposited: 25 Jun 2023 11:19
Last Modified: 25 Jun 2023 11:19
URI: http://repository.unair.ac.id/id/eprint/127589
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