Ketut Suastika, - and Fatimah Eliana, - and Ida Ayu Made Kshanti, - and Mardianto, - and Sony Wibisono Mudjarnako, - and Nanny Natalia, - and Heri Nugrohom HS, - and Roy Panusunan Sibarani, - and Pradana Soewondo, - and Soebagijo Adi Soelistijo, Soebagijo and Tri Juli Edi Tarigan, - and Hendra Zufry, - Expert Opinion on Diabetes Management Challenges and Role of Basal Insulin/GLP-1 RA Fixed-Ratio Combination in People with Type 2 Diabetes from Indonesia. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 15. ISSN 1178-7007

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Abstract

Abstract: Indonesia is struggling with a rapidly growing burden of diabetes due to rapid socioeconomic transition. People with type 2 diabetes mellitus (T2DM) need appropriate treatment strategies to maintain glycemic control. New modalities with simplicity, such as fixed-ratio combination of basal insulin and glucagon-like peptide-1 receptor agonist (GLP-1 RA), further referred to as FRC, have proven to be an effective and practical therapeutic approach that may address this issue. In January 2021, a scientific expert meeting was held with the participation of endocrinologists from Indonesia to provide expert opinions regarding the optimal practical use of the FRC basal insulin/GLP1-RA. Topics discussed in the meeting included the challenges in diabetes management, clinical inertia with insulin therapy, local and international guideline positioning, initiation, titration, and switching of basal insulin and GLP-1 RA, including FRC, and the management of T2DM.

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