Dwi Puspa Sukma Viranda, - (2022) Pengaruh Ekstrak Umbi Porang (Amorphophallus Oncophyllus) Terhadap Histopatologi Testis Tikus Putih (Rattus Norvegicus) Yang Di Induksi Aloksan. Skripsi thesis, UNIVERSITAS AIRLANGGA.

	Text (HALAMAN JUDUL) 061711133052_HALAMAN JUDUL.pdf Download (203kB)
	Text (BAB I) 061711133052_BAB I.pdf Download (79kB)
	Text (FULLTEXT) 061711133052_FULLTEXT.pdf Restricted to Registered users only Download (1MB) | Request a copy

Abstract

"This study was conducted to investigate The Effect of Porang Tuber Extract (Amorphophallus oncophyllus) on the Histopathology of the Testis of White Rats (Rattus norvegicus) Induced by Alloxan. Thirty male rats were divided into six groups and were administered via intragastric gavage with different treatments for 14 days. The treatments were Negative Control (CMC Na 0,5% solution + aquadest), Positive Control (CMC Na 0,5% solution + 120 mg/kgBW alloxan), Drug Control (45 mg/kgBW metformin + 120 mg/kgBW alloxan), Treatmnet 1, 2, and 3 (100, 200, and 400 mg/kgBW of porang tuber extract respectively + 120 mg/kgBW alloxan). Histopathological changes in the testes of white rats were examined by scoring with the Johnsen score criteria and analyzed by Kruskal- Wallis followed by the Mann-Whitney test. Changes in the diameter and thickness of the seminiferous tubular epithelium were measured using imageJ application and analyzed by ANOVA test followed by Duncan test. The results showed that porang tuber extract at a dose of 200 mg/kgBW could improve the histopathology of the white rat testes, diameter, and thickness of the seminiferous tubule epithelium from the damaging effects of alloxan-induced diabetes "

Actions (login required)

View Item