Aurelia Regina (2022) Types and Locations of ST-Segment Changes and Impact on Mortality of COVID-19 Patients in Referral Hospitals in East Java. Skripsi thesis, Universitas Airlangga.

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Abstract

Myocardial injury is one of the most common complications in COVID-19 patients, indicated by ST-segment changes in ECG findings. ST-segment changes were shown to have higher association with severe prognosis and higher mortality rate. With significant association between ST-segment changes and possible prognostic factors in COVID-19 patients, a comprehensive approach is needed to enhance the survival rate through a better understanding of the aforementioned association. We identified 562 confirmed COVID-19 data in East Java between March 2020 to April 2021. Electrocardiograph (ECG) findings of each patient were examined to find which type and location of ST-segment changes were most significantly correlated to mortality. After multivariable adjustment and stepwise elimination, six of 22 variables: gender (p = 0.02), age (p = <0.01), anterior ST elevation (p = <0.01), anteroseptal ST elevation (p = <0.01), upsloping ST depression (p = <0.01), and coronary heart disease (p = 0.04) were found significant towards mortality. We concluded that anterior and anteroseptal ST elevation and upsloping ST depression have worse prognosis thus higher mortality rate in COVID-19 patients compared to other types and locations of ST changes. Further studies are required to enhance the improvement of care coordination.

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