Karta Sudibyo Wangsawidjaja (2015) Potensi Ekstrak B Penurun Kadar Glukosa Darah Buah Strawberry (Fragaria X Ananassa) Sebagai Mencit Model Diabetes Mellitus. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Background : Diabetes mellitus is one of the most common disease in the world nowadays. It caused a lot of death and other disadvantages. Some data about strawberry (Fragaria x ananassa) contains some ingredients that have some clinical potential as anti-cancer, anti-diabetes, anti-hipertension, and antioxidant. Ellagitanin Acid, catechin, and flavonoid are three main chemicals that have potential in reducing blood glucose level. Purpose : To prove the effect of strawberry in reducing blood glucose level and find an natural alternative treatment for diabetes mellitus. Method : This experiment was conducted on 28 male Mus musculus in the age of four to six month with weight between 20 to 30 grams. They were grouped into 1 control group and 3 experimental groups which consist of 7 mice each group. The mice were injected intraperitoneal with 40mg/kg of streptozotocin a day for 5 days in a row to raise blood glucose level. The strawberry extract were given in 3 different doses, 70mg/kg, 140mg/kg, and 280mg/kg. The blood glucose measured after 1 and 2 weeks of experiment. Result : There is no significant reduction of blood glucose in all groups. Conclusion : From this experiment, strawberry extract doesn’t have significant effects on blood glucose level in diabetic mice.

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