NURVITA PUTIH KUSUMARAHAYU, 061011059 (2014) EFEK EKSTRAK MENIRAN (Phyllanthus niruri Linn) SEBAGAI IMUNOMODULATOR TERHADAP DIAMETER PULPA PUTIH LIMPA AYAM BROILER DIINFEKSI Escherichia coli. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

The purpose of this study was to determine the effect of Phyllanthus niruri,. Linn extract supplementation on diameter of spleen white pulp of broiler chickens were infected by Escherichia coli. Twenty five of broiler chickens at 22 days old of Cobb 500 were randomized into 5 treatment groups. Group PO- was fed basal and not infected by Escherichia coli as a control group. Group PO+ was fed basal and infected by 106 Escherichia coli. Group P1 was fed basal and infected by 106 Escherichia coli before supplemented by 20% of Phyllanthus niruri at 23 days old. Group P2 was fed basal and infected by 106 Escherichia coli before supplemented by 25% of Phyllanthus niruri at 23 days old. Group P3 was fed basal and infected by 106 Escherichia coli before supplemented with 30% of Phyllanthus niruri at 23 days old. All of broiler chickens were sacrified at 30 days old. Data was obtained from spleen white pulp diameter and analyzed by ANOVA followed by Duncan test, while the histology of spleen white pulp data were viewed and analyzed by OptiLab Viewer with Image Raster software. The results showed that Phyllanthus niruri can effect on diameter of spleen white pulp infected by Escherichia coli.

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