PREMITA AGUSTINA, 060610276 (2011) PENGARUH PEMBERIAN FRAKSI AIR KULIT BUAH JERUK KEPROK (Citrus nobilis Lour.) TERHADAP GAMBARAN HISTOPATOLOGI GINJAL MENCIT (Mus musculus) JANTAN. Skripsi thesis, UNIVERSITAS AIRLANGGA.
|
Text (ABSTRAK)
gdlhub-gdl-s1-2011-agustinapr-19255-kkckkk-k.pdf Download (483kB) | Preview |
|
![[img]](https://repository.unair.ac.id/style/images/fileicons/text.png) |
Text (FULL TEXT)
gdlhub-gdl-s1-2011-agustinapr-16087-kkckkk-p.pdf Restricted to Registered users only Download (1MB) | Request a copy |
Abstract
This research was to determine the effects of Citrus nobilis Lour. peels water fraction administration on the renal histopathology features of male mice (Mus musculus). Hesperidin of Citrus nobilis Lour. Peels has antifertility activity to reduce hyaluronidase enzyme that produced by sperm. However, saponin of Citrus nobilis Lour. Peels can caused demage to the renal histopatology features. Experimental animals who are used as many as 24 males mice (Mus musculus) with body weight of 30 g and ages of 6 months who were randomly divided into four treatment groups and 6 replication. The control group (P0) were given aquadest 1 ml orally and the treatment group (P1, P2 and P3) were given Citrus nobilis Lour. peels water fraction solution 1 ml orally with a dose 40 mg/ kg body weight, 60 mg/ kg body weight and 80 mg/ kg body weight. All experimental animals were treated for 35 days. Then all the experimental animals leter performed surgery to be taken in order to make preparations renal histopathology. Histopathological examination preparations with a light microscope with 100x magnification and than continued with 400x magnification. The result are analyzed by Kruskal-Wallis test and, if there are differences who significantly (P<0,05) than followed by Mann-Whitney test. The histopathological examination showed that Citrus nobilis Lour. peels water fraction solution with dose of 40 mg/ kg body weight, 60 mg/ kg body weight and 80 mg/ kg body weight during 35 days caused changes in male mice renal histopathology features of congestion and tubular degeneration.
| Item Type: | Thesis (Skripsi) | ||||||
|---|---|---|---|---|---|---|---|
| Additional Information: | KKC KK KH 187/10 Agu p | ||||||
| Uncontrolled Keywords: | MEDICINAL PLANTS; HEART - HISTOPATHOLOGY | ||||||
| Subjects: | R Medicine > RB Pathology > RB37-56.5 Clinical pathology. Laboratory technique S Agriculture > SF Animal culture > SF405.5-407 Laboratory animals |
||||||
| Divisions: | 06. Fakultas Kedokteran Hewan | ||||||
| Creators: |
|
||||||
| Contributors: |
|
||||||
| Depositing User: | mat sjafi'i | ||||||
| Date Deposited: | 23 Jul 2011 12:00 | ||||||
| Last Modified: | 28 Sep 2016 01:57 | ||||||
| URI: | http://repository.unair.ac.id/id/eprint/21236 | ||||||
| Sosial Share: | |||||||
Actions (login required)
 |
View Item |