Puspita Octavia, 060810125 (2012) PENGARUH PEMBERIAN BORAKS TERHADAP GAMBARAN HISTOPATOLOGI HEPAR TIKUS PUTIH (Rattus norvegicus). Skripsi thesis, UNIVERSITAS AIRLANGGA.

Preview	Text (ABSTRAK) gdlhub-gdl-s1-2012-octaviapus-21065-4.ABSTRAK.pdf Download (89kB) | Preview
	Text (FULLTEXT) gdlhub-gdl-s1-2012-octaviapus-21065-1.FULLTEXT.pdf Restricted to Registered users only Download (2MB) | Request a copy

Abstract

The purpose of this study was to evaluate the changes of liver histopathology after giving borax on wistar rats using different dose. The research has been done on February, 6th 2012-March, 8th 2012 at Mulyorejo Utara street number 51A Surabaya and Faculty of Veterinary Medicine, Airlangga University. 20 male rats (Rattus norvegicus strain wistar) aged 45 days with BW 100 g were used. The rats divided into five treatments; rats in one treatments was only given sterile aquadest 0,5 ml/rats/day per oral, second treatment was given with borax 26 mg/rats/day per oral, third treatments was given with borax 52 mg/rats/day per oral, fourth treatments was given with borax 78 mg/rats/day per oral and the last treatmens was given with higher dose of borax was 104 mg/rats/day per oral. The data were compared using ANOVA test (Analisis of variance) and Duncan’s multiple range test. Statistical comparisons were performed using SPSS 18.0 for windows. This research showed that borax failed to caused congestion on liver histopathology on rats but borax caused degeneration and necrosis on liver histopathology.

Actions (login required)

View Item