SITI NURIL MUFARRIHAH AGUSTINA, NIM011314653011 (2016) EFEK PEMBERIAN EKSTRAK TEH HIJAU (Camellia sinensis) TERHADAP ANALISIS SEMEN, DIAMETER TUBULUS SEMINIFERUS, DAN KADAR MALONDIALDEHYDE (MDA) TESTIS MENCIT Balb/c SETELAH DIPAPAR MONOSODIUM GLUTAMATE (MSG). Disertasi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Green tea extract can be used as antioxidant in reducing MSG toxicity. This study aims to prove the difference in concentration, motility, morphology, and viability of sperma, seminiferous tubules diameter, and testicular MDA level of mice exposed to MSG. 25 Balb/c mice divided into 5 groups. Group K- was the control group without administration of MSG and green tea extract. Group K+ was given with MSG of 4 mg/gr BW for 35 days + CMC on days 21-35. Group P1 was given with MSG of 4 mg/gr BW + green tea extract of 200 mg/kg on days 21-35, group P2 was given with MSG 4 mg/gr BW + green tea extract of 400 mg/kg on days 21-35, and P3 group was given with MSG 4 mg/gr BW + green tea extract of 800 mg/kg on days 21-35. The result showed significant differences in the sperm concentration between K+ and P3, significant differences in the sperm motility progressive 3 between K- and K+ K- and P1, K+ and P3, significant differences in the normal-shaped sperm morphology between K- and K+, between K+ and P2 and P3, significant differences in the seminiferous tubules diameter between K- and K+ and P1, between K+ and P3, significant differences in the testes MDA levels between K- and K+, and between K+ and P3. It is concluded that there were significant differences sperm concentration, sperm motility progressive 3, normal sperm morphology, sperm viability, seminiferous tubulus diameter, and testicular MDA levels between K-, K+, P1, P2, and P3.

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