SULASMI, 101141010 (2013) EFEK PENAMBAHAN VITAMIN C PADA SUPLEMENTASI FE +FOLAT TERHADAP KADAR FERITIN DAN HEMOGLOBIN IBU HAMIL ANEMIA (Studi di Kecamatan Sawahan Kota Surabaya). Thesis thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Iron deficiency anemia is the most common disorders during pregnancy. Vitamin C and iron are expected to overcome anemia. The study was conducted to determine the effect of vitamin C addition on Fe + folate supplementation related to ferritin and hemoglobin levels. This research was an experimental study with Pre Test-Post Test Control Group Design. The treatment group were given vitamin C (50 mg) and Fe + folate (60 mg + 200 mg), a control group were given Fe + Folate (60 mg + 200 mg). Supplementation was given over 12 weeks and consumed every day. Ferritin and hemoglobin samples were collected 2 times at before and after treatment. Ferritin level was determined with Enzyme-Linked Immunosorbent Assays (ELISA) at Klinika laboratory Surabaya. Haemoglobin were analyzed by standard Cyanmethemoglobin method at Pakis Health Centre laboratory. Data were analyzed using t-test. The results showed significant differences of ferritin levels after treatment between the treatment group and the control group (p = 0.010) and nothing difference hemoglobin levels before and after treatment in the treatment group (p = 0.018). There was not only differences hemoglobin levels before and after treatment in the control group (p = 0.001), but also nothing significant difference after treatment and the control group (p = 0.979). Conclusion, there is a significant effect of vitamin C addition on Fe + folate supplementation for increasing levels of ferritin but no significant effect on hemoglobin levels.

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