FATINATUL ISTIQOMAH, 051211133025 (2016) UJI HAMBAT TIROSINASE EKSTRAK TOMAT DALAM SISTEM PENGHANTAR NANOSTRUCTURED LIPID CARRIER DAN SOLID LIPID NANOPARTICLE (Basis Lipid Setil Alkohol : Isopropil Miristat 9 : 1). Skripsi thesis, Universitas Airlangga.

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Abstract

This study aimed to compare the effectiveness of tomato extract on the system NLC and SLN as a skin-lightening preparations in terms of testing the tyrosinase inhibitory activity in vitro. The method of making NLC and SLN was done by high shear hot homogenization speed of 24000 rpm for 4 cycles. Characterization of the samples was conducted on the organoleptic observation, examination of particle size and particle size homogeneity (DelsaTM Nano), the determination of pH (pH meter), viscosity (Brookfield Cone and Plate viscometer), and determining the pattern of diffraction (XRay Powder Diffraction). Testing characteristics of the preparations carried out at different times, which is 7 and 28 days after manufacture to determine the stability of the preparation over time. Keywords: lycopene, tomato extract, NLC, SLN, tyrosinase inhibitory

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