Dihydroflavonols from the leaves of Macaranga recurvata and their cytotoxic and antioxidant activities.

Mulyadi, Tanjung and Tjahjandarie, Tjitjik Srie (2014) Dihydroflavonols from the leaves of Macaranga recurvata and their cytotoxic and antioxidant activities. Journal of Chemical and Pharmaceutical Research, 6 (7). pp. 90-95. ISSN 0975-7384

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Abstract

Three dihydroflavonol derivatives, macarecurvatin A (1), macarecurvatin B (2), and 6,8-diisoprenylaromadendrin (3) have been isolated from the leaves of Macaranga recurvata. The structures of these compounds were determined based on UV, IR, HRESIMS, 1D and 2D NMR data. All of compound isolated were evaluated for their inhibitory effect on scavenging DPPH radical and their growth inhibition on MCF7, and tamoxifen-resistant MCF7(MCF7/TAMR) breast cancer cell showed high antioxidant and high cytotoxic activities.

Item Type: Article
Uncontrolled Keywords: Macarecurvatin A and B, 6,8-Diisoprenylaromadendrin, Dihyroflavonol, Macaranga recurvata,Antioxidant,Cytotoxic
Subjects: Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsNIM
Mulyadi, TanjungUNSPECIFIED
Tjahjandarie, Tjitjik SrieUNSPECIFIED
Depositing User: Mr Akhmad Nurfizal Reza
Date Deposited: 12 Oct 2017 20:17
Last Modified: 12 Oct 2017 20:22
URI: http://repository.unair.ac.id/id/eprint/63032
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